N-Alkylphtalimides are intermediates in the synthesis of primary amines1 and are generally prepared from potassium phtalimide and alkyl halides in anhydrous polar aprotic solvents such as dimethylformamide.2 Recently, N-alkylation of potassium phtalimide has been achieved from alkyl halides and methanesulfonates in toluene in the presence of hexadecyltributylphosphonium bromide3.

Preparation of N-alkylphthalimides assisted by solid-liquid phase-transfer systems / E. Santaniello, F. Ponti. - In: SYNTHETIC COMMUNICATIONS. - ISSN 0039-7911. - 10:8(1980), pp. 611-614.

Preparation of N-alkylphthalimides assisted by solid-liquid phase-transfer systems

E. Santaniello
Primo
;
1980

Abstract

N-Alkylphtalimides are intermediates in the synthesis of primary amines1 and are generally prepared from potassium phtalimide and alkyl halides in anhydrous polar aprotic solvents such as dimethylformamide.2 Recently, N-alkylation of potassium phtalimide has been achieved from alkyl halides and methanesulfonates in toluene in the presence of hexadecyltributylphosphonium bromide3.
Settore BIO/10 - Biochimica
1980
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/195404
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