Neonatal lupus erythematosus (NLE) is a rare disorder. It is characterized by cutaneous lesions and/or congenital heart block. Hematological abnormalities can be associated. The disorder is due to transplacental passage of anti-Ro/SSA and, less frequently, anti-La/SSB antibodies. A case of neonatal lupus erythematosus in a male child, who was born to a mother with Sjogren syndrome, is reported. The case was clinically characterized by persistent, punctiform telangiectases of the eyelids and, serologically, by increased level of autoantibodies to native 60-kd Ro/SSA, in spite of lacking heart involvement
Neonatal lupus erythematosus with persistent cutaneous telangiectases / S. Menni, G. Tribbia. - In: PD. EUROPEAN JOURNAL OF PEDIATRIC DERMATOLOGY. - ISSN 1122-7788. - 8:4(1998), pp. 205-208.
Neonatal lupus erythematosus with persistent cutaneous telangiectases
S. MenniPrimo
;
1998
Abstract
Neonatal lupus erythematosus (NLE) is a rare disorder. It is characterized by cutaneous lesions and/or congenital heart block. Hematological abnormalities can be associated. The disorder is due to transplacental passage of anti-Ro/SSA and, less frequently, anti-La/SSB antibodies. A case of neonatal lupus erythematosus in a male child, who was born to a mother with Sjogren syndrome, is reported. The case was clinically characterized by persistent, punctiform telangiectases of the eyelids and, serologically, by increased level of autoantibodies to native 60-kd Ro/SSA, in spite of lacking heart involvementPubblicazioni consigliate
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