BACKGROUND: The study was carried out to value the analgesic efficacy of ketoprofen lysinate solution administered by oral route. Ketoprofen lysinate solution is an efficacious topical drug for pain relief and control of inflammation agents. METHODS: The study was carried out in 120 patients submitted to orthodotic therapy by oral route, under single blind conditions at the "San Raffaele" Hospital in Milan. The 120 patients who underwent orthodonthic therapy were males and females, from 18 to 40 years old. One group was treated with ketoprofen lysinate solution at the doses of 160 mg in 100 ml (60 patients), the other group with benzidamine hydrochloride 15 ml (60 patients), twice a day for seven days. Pain relief and control of inflammation agents have been evaluated. RESULTS: The study showed ketoprofen lysinate solution to be very effective for pain relief and control of inflammation agents. In fact, on the basis of the visual analogue scale of Scott-Huskisson and of the patient's judgement, ketoprofen proved significantly better than benzidamine. CONCLUSIONS: The analgesic efficacy of ketoprofen lysinate solution administered by oral route was prompt and long lasting than benzidamine. Both treatments were very well tolerated.
|Titolo:||Efficacia e tollerabilità nel ketoprofene sale di lisina ad uso topico nelle flogosi acute del cavo orale in corso di terapia ortognatodontica. Studio randomizzato, in singolo cieco, per gruppi paralleli verso benzidamina cloridrato.|
SPADARI, FRANCESCO (Secondo)
SALVATO, ANTONINO (Ultimo)
|Settore Scientifico Disciplinare:||Settore MED/28 - Malattie Odontostomatologiche|
|Data di pubblicazione:||2000|
|Appare nelle tipologie:||01 - Articolo su periodico|