The 20 letters lattice model of proteins is reviewed. Following this, the question of protein designability is addressed. Finally, the quantitative, analytic answer to the question of how many mutations a designed protein tolerates is highlighted.
Designability of lattice model heteropolymers / G. Tiana, R. A. Broglia , D. Provasi. - In: PHYSICAL REVIEW E, STATISTICAL, NONLINEAR, AND SOFT MATTER PHYSICS. - ISSN 1539-3755. - 64:1(2001), pp. 11904.1-11904.6.
Designability of lattice model heteropolymers
G. TianaPrimo
;
2001
Abstract
The 20 letters lattice model of proteins is reviewed. Following this, the question of protein designability is addressed. Finally, the quantitative, analytic answer to the question of how many mutations a designed protein tolerates is highlighted.
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