TGPO autoantibodies (aAbs) that bind simultaneously to thyroglobulin (Tg) and thyroperoxidase (TPO) are present in the serum of patients with autoimmune thyroid diseases (AITD) and have been found to differ from monospecific Tg and TPO aAbs. To obtain further insights on the prevalence defined as the rate of occurrence and significance of TGPO aAbs in a large population, we carried out a collaborative study involving 15 European teams.

Multicenter study on TGPO autoantibody prevalence in various thyroid and non-thyroid diseases; relationships with thyroglobulin and thyroperoxidase autoantibody parameters / V. Estienne, C. Duthoit, V. D. Costanzo, P. J. Lejeune, M. Rotondi, S. Kornfeld, R. Finke, J. H. Lazarus, U. Feldt-Rasmussen, W. G. Franke, P. Smyth, M. D'Herbomez, B. Conte-Devolx, L. Persani, C. Carella, J. R. Jourdain, M. Izembart, M. E. Toubert, A. Pinchera, A. Weetman, R. Sapin, P. Carayon, J. Ruf. - In: EUROPEAN JOURNAL OF ENDOCRINOLOGY. - ISSN 0804-4643. - 141:6(1999 Dec), pp. 563-9-569.

Multicenter study on TGPO autoantibody prevalence in various thyroid and non-thyroid diseases; relationships with thyroglobulin and thyroperoxidase autoantibody parameters

L. Persani;
1999

Abstract

TGPO autoantibodies (aAbs) that bind simultaneously to thyroglobulin (Tg) and thyroperoxidase (TPO) are present in the serum of patients with autoimmune thyroid diseases (AITD) and have been found to differ from monospecific Tg and TPO aAbs. To obtain further insights on the prevalence defined as the rate of occurrence and significance of TGPO aAbs in a large population, we carried out a collaborative study involving 15 European teams.
Reagent Kits, Diagnostic; Autoimmune Diseases; Thyroglobulin; Puerperal Disorders; Autoantibodies; Humans; Graves Disease; Thyroiditis, Autoimmune; Iodide Peroxidase; Thyroid Diseases; Female; Pregnancy
Settore MED/13 - Endocrinologia
dic-1999
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/193837
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