The title polymers having a single reactive moiety at one end of the polymer chain have the following structure R-Z-X-Y (R = N-acryloylmorpholine residue with d.p. 6-280, which yields no.-av. mol. wt. 1000-40,000; Z-X-Y = polymer capping moiety; X = satd. residue of linear or branched aliph. series CrH2r, r = 1-12; Y = reactive moiety, such as -OH, -CO2H, or -NH2; Z = moiety that readily reacts to cap a polymer free radical, e.g., S). The monofunctional polymer is a suitable alternative to monofunctional PEG for modification of substances having biol. and biotech. applications.
Polymers of N-acryloylmorpholine derivative activated at one end and conjugates with bioactive materials and surfaces / V. M. F, S. O., C. P., S. L., E. Ranucci, F. P..
Polymers of N-acryloylmorpholine derivative activated at one end and conjugates with bioactive materials and surfaces
E. Ranucci;
1997
Abstract
The title polymers having a single reactive moiety at one end of the polymer chain have the following structure R-Z-X-Y (R = N-acryloylmorpholine residue with d.p. 6-280, which yields no.-av. mol. wt. 1000-40,000; Z-X-Y = polymer capping moiety; X = satd. residue of linear or branched aliph. series CrH2r, r = 1-12; Y = reactive moiety, such as -OH, -CO2H, or -NH2; Z = moiety that readily reacts to cap a polymer free radical, e.g., S). The monofunctional polymer is a suitable alternative to monofunctional PEG for modification of substances having biol. and biotech. applications.Pubblicazioni consigliate
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