In this paper, reported are results on the preparation of new amphiphilic oligomers of N-acryloylmorpholine (ACM) and N-vinylpyrrolidinone (VP) carrying terminal functions such as primary hydroxyl groups in the case of poly(N-vinyl pyrrolidinone) (PVP), and primary hydroxyl-, carboxyl-, and amino groups in the case of poly(N-acryloyl morpholine) (PACM). PVP is well known for its amphiphilic properties and lack of toxicity. PACM is also non-toxic and in a crosslinked form was used as support matrix for solid phase synthesis of peptides.
End-functionalized amphiphilic oligomers / E. RANUCCI, G. Spagnoli, I. Peroni, Sartore L., P. Ferruti, Veronese, F. M.. - In: MACROMOLECULAR REPORTS. - ISSN 1060-278X. - A31:6-7(1994), pp. 831-834.
End-functionalized amphiphilic oligomers
E. RANUCCIPrimo
;
1994
Abstract
In this paper, reported are results on the preparation of new amphiphilic oligomers of N-acryloylmorpholine (ACM) and N-vinylpyrrolidinone (VP) carrying terminal functions such as primary hydroxyl groups in the case of poly(N-vinyl pyrrolidinone) (PVP), and primary hydroxyl-, carboxyl-, and amino groups in the case of poly(N-acryloyl morpholine) (PACM). PVP is well known for its amphiphilic properties and lack of toxicity. PACM is also non-toxic and in a crosslinked form was used as support matrix for solid phase synthesis of peptides.
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