Background. The double action - antimycotic and anti-inflammatory - of itraconazole, has opened new horizons in the treatment of a number of inflammatory skin disorders in which Malassezia yeasts seem to play a pathogenetic role. Methods. An open study was carried out on 185 patients, including: 160 patients affected by seborrhoeic dermatitis; 5 patients with Malassezia folliculitis; 8 patients with peri-oral dermatitis and papulo-pustular rosacea; 6 patients with adult atopic dermatitis of the face and the neck; and 6 patients with palmoplantar amicrobic pustulosis. In all patients the basic treatment schedule was itraconazole 200 mg/day for 7 days. Results. A marked reduction of signs and symptoms of these diseases was obtained. Conclusions. Itraconazole is a drug to be considered in the treatment of this group of conditions, particularly for seborrhoeic dermatitis and Malassezia folliculitis.

Itraconazole: new horizons / R. Caputo, M. Barbareschi, A. Gorani, S. Veraldi. - In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - ISSN 0926-9959. - 16:suppl. 1(2002), pp. 254-254. ((Intervento presentato al 11. convegno Congress of the European Academy of Dermatology & Venereology.

Itraconazole: new horizons

M. Barbareschi
Secondo
;
S. Veraldi
Ultimo
2002

Abstract

Background. The double action - antimycotic and anti-inflammatory - of itraconazole, has opened new horizons in the treatment of a number of inflammatory skin disorders in which Malassezia yeasts seem to play a pathogenetic role. Methods. An open study was carried out on 185 patients, including: 160 patients affected by seborrhoeic dermatitis; 5 patients with Malassezia folliculitis; 8 patients with peri-oral dermatitis and papulo-pustular rosacea; 6 patients with adult atopic dermatitis of the face and the neck; and 6 patients with palmoplantar amicrobic pustulosis. In all patients the basic treatment schedule was itraconazole 200 mg/day for 7 days. Results. A marked reduction of signs and symptoms of these diseases was obtained. Conclusions. Itraconazole is a drug to be considered in the treatment of this group of conditions, particularly for seborrhoeic dermatitis and Malassezia folliculitis.
Atopic dermatitis; Itraconazole; Malassezia folliculitis; Palmoplantar amicrobic pustulosis; Papulo-pustular rosacea; Perioral dermatitis; Seborrhoeic dermatitis
Settore MED/35 - Malattie Cutanee e Veneree
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/192771
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