Esophageal injuries caused by oral medications have recently been recognized as a iatrogenic entity. This pathogenesis is due to the retention in the esophagus of drugs with caustic properties. The main predisposing factor is the practice of taking oral drugs with a small quantity of water of and/or in a recumbent position. Elderly subjects and patients with pre-existing esophageal disorders are at higher risk, so that fluid formulations or different routes of drug administration are strongly recommended. A more widespread education to the correct use of drugs and a better drug formulation are necessary for effective prevention.
|Titolo:||[Esophageal lesions caused by oral drugs. Epidemiology, physiopathologic bases, prospectives of prevention]|
BONAVINA, LUIGI (Primo)
|Parole Chiave:||Esophagus; Administration, Oral; Drug Therapy; Hydrogen-Ion Concentration; Humans; Burns, Chemical; Posture; Deglutition|
|Settore Scientifico Disciplinare:||Settore MED/18 - Chirurgia Generale|
|Data di pubblicazione:||15-gen-1987|
|Appare nelle tipologie:||01 - Articolo su periodico|