Compounds of the general formula (I) and (II) (including formulae (III) to (V)), wherein X=-CH2-, -O-, -S- n=0-10 Y=-NH-, -NHSO2-, -NHSO-, -NHCO-, -S-, -O-, -CH-CH-R1-R7, equal or different can be hydrogen, alkyl C1-C4, alkenyl C2-C4, cycloalkyl C3-C7, aryl or heteroaryl; may be substituted with one or more alkyl C1-C4, alkoxyl C1-C4, alkylthio C1-C4 or halogens; -NR8R9, where R8 e R9, equal or different, represent hydrogen, alkyl C1-C4, alkenyl C2-C4, cycloalkyl C3-C7, aryl or heteroaryl, may be substituted with one or more C1-C4, alkoxyl C1-C4, alkylthio C1-C4 or halogens; -(CH2)n, -COOR10, with n'=0-4 and R3=hydrogen or alkyl C1-C4, and their addition salts with organic and inorganic acids, or alkaline and alkaline earth metal or ammonium ions, with the exclusion of the compounds having the following formulae ((VI) to (IX)).

Compound with glycidic structure active in the therapy of systemic and local inflammation / C. Rumio, A. Balsari, M. Palazzo, F. Nicotra, B. La Ferla.

Compound with glycidic structure active in the therapy of systemic and local inflammation

C. Rumio;A. Balsari;
2011

Abstract

Compounds of the general formula (I) and (II) (including formulae (III) to (V)), wherein X=-CH2-, -O-, -S- n=0-10 Y=-NH-, -NHSO2-, -NHSO-, -NHCO-, -S-, -O-, -CH-CH-R1-R7, equal or different can be hydrogen, alkyl C1-C4, alkenyl C2-C4, cycloalkyl C3-C7, aryl or heteroaryl; may be substituted with one or more alkyl C1-C4, alkoxyl C1-C4, alkylthio C1-C4 or halogens; -NR8R9, where R8 e R9, equal or different, represent hydrogen, alkyl C1-C4, alkenyl C2-C4, cycloalkyl C3-C7, aryl or heteroaryl, may be substituted with one or more C1-C4, alkoxyl C1-C4, alkylthio C1-C4 or halogens; -(CH2)n, -COOR10, with n'=0-4 and R3=hydrogen or alkyl C1-C4, and their addition salts with organic and inorganic acids, or alkaline and alkaline earth metal or ammonium ions, with the exclusion of the compounds having the following formulae ((VI) to (IX)).
Rumio C
Balsari A
Palazzo A
La Ferla B
Nicotra F
US2011/0112184
US12/991,455
12-mag-2011
Settore BIO/16 - Anatomia Umana
Compound with glycidic structure active in the therapy of systemic and local inflammation / C. Rumio, A. Balsari, M. Palazzo, F. Nicotra, B. La Ferla.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/192289
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