6 patients are described who developed contact dermatitis after cereal contact on atopic skin for periods of 2 to 20 years. 2 patients were wheat flour patch-test-positive. They had punch biopsies taken for standard histological and immunohistochemical investigation by labeling with monoclonal antibodies, anti-DR and anti-IgE. Sections showed features of contact dermatitis. There were many dendritic cells located perivascularly in the papilla and in the epidermidis, intensely positive for monoclonal anti-IgE antibody. In control atopic subjects, there were a few perivascular IgE positive cells, probably mastocytes. This study shows that there may be a relationship between some allergens and atopic eczema in patients exposed to them in the course of their work. In some cases, there was a true allergic contact dermatitis, seen through the clinical and histological characteristics, and the results of immunohistochemical study.
|Titolo:||Occupational dermatitis in bakers: a clue for atopic contact dermatitis|
PIGATTO, PAOLO DANIELE MARIA (Primo)
ALTOMARE, GIANFRANCO (Ultimo)
|Parole Chiave:||Triticum; Skin; Dermatitis, Atopic; Skin Tests; Immunoglobulin E; Humans; Adult; Food Handling; Dermatitis, Occupational; Biopsy; Male; Flour|
|Settore Scientifico Disciplinare:||Settore MED/35 - Malattie Cutanee e Veneree|
|Data di pubblicazione:||mag-1987|
|Appare nelle tipologie:||01 - Articolo su periodico|