An intensified CCD video camera has been used to measure the spatial distribution of the fluorescence decay time in tumor-bearing mice sensitized with hematoporphyrin derivative. Mice were injected with five doses of sensitizer, ranging from 0.1 to 10 mg/kg body weight. For any drug dose the decay time of the exogenous fluorescence in the tumor is always significantly longer than in normal tissues. The image created by associating a gray-shade scale to the decay time matrix of each mouse permits a reliable and precise detection of the neoplasia
Tumor detection in mice by measurement of fluorescence decay time matrices / R. Cubeddu, A. Pifferi, P. Taroni, G. Valentini, G. Canti. - In: OPTICS LETTERS. - ISSN 0146-9592. - 20:24(1995 Dec 15), p. 2553.
|Titolo:||Tumor detection in mice by measurement of fluorescence decay time matrices|
CANTI, GIANFRANCO (Ultimo)
|Settore Scientifico Disciplinare:||Settore BIO/14 - Farmacologia|
|Data di pubblicazione:||15-dic-1995|
|Appare nelle tipologie:||01 - Articolo su periodico|