Mitotic cultures synchronised either by a feed-starve protocol or by elutriation have been used to show that the Saccharomyces cerevisiae DNA primase I gene is periodically expressed in the cell cycle. The transcript increases many-fold in late G1 and reaches a peak at the same time as four other genes essential for DNA synthesis, CDC8, CDC9, CDC21 and POL1. The primase I transcript is also regulated in meiosis, reaching maximal levels during premeiotic DNA synthesis.
Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis / L. H. Johnston, J. H. White, A. L. Johnson, G. Lucchini, P. Plevani. - In: MOLECULAR AND GENERAL GENETICS. - ISSN 0026-8925. - 221:1(1990 Mar), pp. 44-8-48.
Expression of the yeast DNA primase gene, PRI1, is regulated within the mitotic cell cycle and in meiosis
P. PlevaniUltimo
1990
Abstract
Mitotic cultures synchronised either by a feed-starve protocol or by elutriation have been used to show that the Saccharomyces cerevisiae DNA primase I gene is periodically expressed in the cell cycle. The transcript increases many-fold in late G1 and reaches a peak at the same time as four other genes essential for DNA synthesis, CDC8, CDC9, CDC21 and POL1. The primase I transcript is also regulated in meiosis, reaching maximal levels during premeiotic DNA synthesis.Pubblicazioni consigliate
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