We report a case of right arm paresis in a parenteral drug addict suffering from acute non-A, non-B hepatitis. His hepatic and neurological symptoms developed together with high level of circulating immune complexes, complement activation, and false VDRL positivity. Immunological abnormalities normalized with the resolution of acute hepatitis and improvement of paresis. These results suggest that neurological dysfunctions may complicate non-A, non-B hepatitis. Moreover, we postulate an immune-mediated mechanism for neuropathy, via a neuropathic activity of circulating immune complexes.

Brachial paresis complicating acute non-A, non-B hepatitis / G. Del Giudice, M. Galli, M. Chemotti, M. Gasparro, F. Franzetti, A. Lazzarin. - In: BOLLETTINO DELL'ISTITUTO SIEROTERAPICO MILANESE. - ISSN 0021-2547. - 63:6(1984), pp. 499-504.

Brachial paresis complicating acute non-A, non-B hepatitis

M. Galli
Secondo
;
A. Lazzarin
Ultimo
1984

Abstract

We report a case of right arm paresis in a parenteral drug addict suffering from acute non-A, non-B hepatitis. His hepatic and neurological symptoms developed together with high level of circulating immune complexes, complement activation, and false VDRL positivity. Immunological abnormalities normalized with the resolution of acute hepatitis and improvement of paresis. These results suggest that neurological dysfunctions may complicate non-A, non-B hepatitis. Moreover, we postulate an immune-mediated mechanism for neuropathy, via a neuropathic activity of circulating immune complexes.
Acute Disease; Injections, Intravenous; Humans; Hepatitis, Viral, Human; Arm; Paralysis; Adult; Substance-Related Disorders; Hepatitis C; Male; Antigen-Antibody Complex; Complement Activation; Immunoglobulins
Settore MED/17 - Malattie Infettive
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/190517
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