A theoretical model for studying RNA base pairing is presented, based on similarity measures of the bases and corresponding indexes. Similarity calculations are made by evaluating atomic importance in molecules, a method that uses an original method for the calculation of electronic energy. The application of the model to both Watson-Crick and non-Watson-Crick pairings is commented on. Some theoretical considerations concerning the capability of the genetic code to repair dangerous mutations contribute to the ongoing debate.

Analysis of a Theoretical Model Based on Similarity for Studying RNA Base Pairings / P. Di Gennaro, G.G. Sello, M. Termini. - In: JOURNAL OF THEORETICAL BIOLOGY. - ISSN 0022-5193. - 181:4(1996 Aug 21), pp. 359-371.

Analysis of a Theoretical Model Based on Similarity for Studying RNA Base Pairings

G.G. Sello
Secondo
;
1996

Abstract

A theoretical model for studying RNA base pairing is presented, based on similarity measures of the bases and corresponding indexes. Similarity calculations are made by evaluating atomic importance in molecules, a method that uses an original method for the calculation of electronic energy. The application of the model to both Watson-Crick and non-Watson-Crick pairings is commented on. Some theoretical considerations concerning the capability of the genetic code to repair dangerous mutations contribute to the ongoing debate.
Settore CHIM/06 - Chimica Organica
Settore BIO/10 - Biochimica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/190178
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