A theoretical model for studying RNA base pairing is presented, based on similarity measures of the bases and corresponding indexes. Similarity calculations are made by evaluating atomic importance in molecules, a method that uses an original method for the calculation of electronic energy. The application of the model to both Watson-Crick and non-Watson-Crick pairings is commented on. Some theoretical considerations concerning the capability of the genetic code to repair dangerous mutations contribute to the ongoing debate.
Analysis of a Theoretical Model Based on Similarity for Studying RNA Base Pairings / P. Di Gennaro, G.G. Sello, M. Termini. - In: JOURNAL OF THEORETICAL BIOLOGY. - ISSN 0022-5193. - 181:4(1996 Aug 21), pp. 359-371.
Titolo: | Analysis of a Theoretical Model Based on Similarity for Studying RNA Base Pairings |
Autori: | SELLO, GUIDO GIOVANNI (Secondo) |
Settore Scientifico Disciplinare: | Settore CHIM/06 - Chimica Organica Settore BIO/10 - Biochimica |
Data di pubblicazione: | 21-ago-1996 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1006/jtbi.1996.0137 |
Appare nelle tipologie: | 01 - Articolo su periodico |