T-lymphocyte subsets and serum immunoglobulins were assayed in 27 neonates and 12 infants younger than 6 months, all born to HIV-seropositive mothers. No differences in T-lymphocyte subsets between the 27 seropositive and 34 seronegative infants were found at birth. Twelve seroreverted and 14 infected children were followed. CD4+ cell counts were significantly lower in the latter at 3 and 24 months of age. Serum immunoglobulin levels and CD8+ percentages became higher in the infected group, starting from the sixth month, while CD4+ percentages and CD4+/CD8+ ratios became lower, starting from the twelfth month.
T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers : a longitudinal evaluation / A. d'Arminio Monforte, R. Novati, M. Galli, P. Marchisio, E. Massironi, R. Tornaghi, A. Saracco, N. Principi, M. Moroni. - In: AIDS. - ISSN 0269-9370. - 4:11(1990 Nov), pp. 1141-1144.
T-cell subsets and serum immunoglobulin levels in infants born to HIV-seropositive mothers : a longitudinal evaluation
A. d'Arminio MonfortePrimo
;M. Galli;P. Marchisio;N. PrincipiPenultimo
;M. MoroniUltimo
1990
Abstract
T-lymphocyte subsets and serum immunoglobulins were assayed in 27 neonates and 12 infants younger than 6 months, all born to HIV-seropositive mothers. No differences in T-lymphocyte subsets between the 27 seropositive and 34 seronegative infants were found at birth. Twelve seroreverted and 14 infected children were followed. CD4+ cell counts were significantly lower in the latter at 3 and 24 months of age. Serum immunoglobulin levels and CD8+ percentages became higher in the infected group, starting from the sixth month, while CD4+ percentages and CD4+/CD8+ ratios became lower, starting from the twelfth month.Pubblicazioni consigliate
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