Intrauterine growth restriction is an important cause of morbidity and mortality. Its pathogenesis is still a matter of debate. The aim of this study was to evaluate the association between intrauterine growth restriction (diagnosed in utero by serial ultrasound examinations and characterized by abnormal umbilical arterial Doppler velocimetry) and thrombophilic polymorphisms (factor V Leiden, prothrombin G20210A) or methylenetetrahydrofolate reductase C677T carried by mothers and/or neonates.
Intrauterine growth restriction and genetic predisposition to thrombophilia / F. Franchi, I. Cetin, T. Todros, P. Antonazzo, M. S. Nobile de Santis, S. Cardaropoli, P. Bucciarelli, E. Biguzzi. - In: HAEMATOLOGICA. - ISSN 0390-6078. - 89:4(2004 Apr), pp. 444-449.
Intrauterine growth restriction and genetic predisposition to thrombophilia
I. CetinSecondo
;P. Antonazzo;M. S. Nobile de Santis;
2004
Abstract
Intrauterine growth restriction is an important cause of morbidity and mortality. Its pathogenesis is still a matter of debate. The aim of this study was to evaluate the association between intrauterine growth restriction (diagnosed in utero by serial ultrasound examinations and characterized by abnormal umbilical arterial Doppler velocimetry) and thrombophilic polymorphisms (factor V Leiden, prothrombin G20210A) or methylenetetrahydrofolate reductase C677T carried by mothers and/or neonates.
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