Thymostimulin (TP-1), a parenterally administered calf thymus extract, has induced a significant increase of OKT4+ peripheral cells in 9 drug addicts with persistent generalized lymphadenopathy; OKT4+ lymphocytes decreased gradually after withdrawal of treatment. In a control group, a spontaneous decrease occurred in the same period of observation. A more prolonged treatment should be undertaken to assess the effectiveness of the drug on the evolution of the disease.
|Titolo:||Increase of OKT4+ cells during treatment with thymostimulin in parenteral drug addicts with persistent generalized lymphadenopathy|
|Parole Chiave:||Antibodies, Monoclonal; T-Lymphocytes, Regulatory; Humans; Immunoblastic Lymphadenopathy; Adult; Substance-Related Disorders; T-Lymphocytes, Helper-Inducer; Thymus Extracts; Male; T-Lymphocytes|
|Settore Scientifico Disciplinare:||Settore MED/17 - Malattie Infettive|
|Data di pubblicazione:||giu-1986|
|Appare nelle tipologie:||01 - Articolo su periodico|