Thymostimulin (TP-1), a parenterally administered calf thymus extract, has induced a significant increase of OKT4+ peripheral cells in 9 drug addicts with persistent generalized lymphadenopathy; OKT4+ lymphocytes decreased gradually after withdrawal of treatment. In a control group, a spontaneous decrease occurred in the same period of observation. A more prolonged treatment should be undertaken to assess the effectiveness of the drug on the evolution of the disease.

Increase of OKT4+ cells during treatment with thymostimulin in parenteral drug addicts with persistent generalized lymphadenopathy / A. Lazzarin, M. Galli, P. Moriondo, C. Parravicini, G. Poli, M. Moroni. - In: JOURNAL OF CLINICAL & LABORATORY IMMUNOLOGY. - ISSN 0141-2760. - 20:2(1986 Jun), pp. 57-61.

Increase of OKT4+ cells during treatment with thymostimulin in parenteral drug addicts with persistent generalized lymphadenopathy

A. Lazzarin;M. Galli;M. Moroni
1986-06

Abstract

Thymostimulin (TP-1), a parenterally administered calf thymus extract, has induced a significant increase of OKT4+ peripheral cells in 9 drug addicts with persistent generalized lymphadenopathy; OKT4+ lymphocytes decreased gradually after withdrawal of treatment. In a control group, a spontaneous decrease occurred in the same period of observation. A more prolonged treatment should be undertaken to assess the effectiveness of the drug on the evolution of the disease.
Antibodies, Monoclonal; T-Lymphocytes, Regulatory; Humans; Immunoblastic Lymphadenopathy; Adult; Substance-Related Disorders; T-Lymphocytes, Helper-Inducer; Thymus Extracts; Male; T-Lymphocytes
Settore MED/17 - Malattie Infettive
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/189247
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