To determine the role of the two angiogenic peptides, vascular endothelial growth factor (VEGF) and thymidine phosphorylase (TP) (the latter also being a target enzyme for cytotoxicity of 5-fluorouracil and methotrexate), and conventional prognostic factors in predicting relapse-free survival (RFS) and overall survival (OS) probabilities in two cohorts of patients with node-positive breast cancer (NPBC) treated with either adjuvant chemotherapy (CMF [cyclophosphamide, methotrexate, 5-fluorouracil] schedule) or hormone therapy (tamoxifen).

Clinical relevance of vascular endothelial growth factor and thymidine phosphorylase in patients with node-positive breast cancer treated with either adjuvant chemotherapy or hormone therapy / G. Gasparini, M. Toi, R. Miceli, P. B. Vermeulen, R. Dittadi, E. Biganzoli, A. Morabito, M. Fanelli, C. Gatti, H. Suzuki, T. Tominaga, L. Y. Dirix, M. Gion. - In: CANCER JOURNAL FROM SCIENTIFIC AMERICAN. - ISSN 1081-4442. - 5:2(1999), pp. 101-11-111.

Clinical relevance of vascular endothelial growth factor and thymidine phosphorylase in patients with node-positive breast cancer treated with either adjuvant chemotherapy or hormone therapy

E. Biganzoli;
1999

Abstract

To determine the role of the two angiogenic peptides, vascular endothelial growth factor (VEGF) and thymidine phosphorylase (TP) (the latter also being a target enzyme for cytotoxicity of 5-fluorouracil and methotrexate), and conventional prognostic factors in predicting relapse-free survival (RFS) and overall survival (OS) probabilities in two cohorts of patients with node-positive breast cancer (NPBC) treated with either adjuvant chemotherapy (CMF [cyclophosphamide, methotrexate, 5-fluorouracil] schedule) or hormone therapy (tamoxifen).
Angiogenic peptides; Breast cancer; Prognosis; Thymidine phosphorylase; Vascular endothelial growth factor
Settore MED/01 - Statistica Medica
CANCER JOURNAL FROM SCIENTIFIC AMERICAN
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/189066
Citazioni
  • ???jsp.display-item.citation.pmc??? 19
  • Scopus 120
  • ???jsp.display-item.citation.isi??? ND
social impact