The relationship between breast cancer, liposoluble vitamins, cholesterol and triglycerides was investigated by means of a hospital-based case-control study conducted at Milan (Italy) and Montpellier (France). These parameters were measured in blood samples taken from 319 cases and 344 controls. The interview included an evaluation of dietary intake of liposoluble vitamins. No difference emerged in liposoluble vitamin consumption, whereas a statistically significantly higher serum level of cholesterol and plasma level of vitamin E existed in cases compared to controls. The difference in plasma vitamin E was confirmed after adjustment for total cholesterol and triglycerides. In contrast, vitamin A variations appear to follow triglyceride trends. A multivariate analysis of the vitamin E plasma level was performed after classification of cases and controls according to quintile distribution of controls. All known risk factors plus age, serum total cholesterol and triglycerides were used as covariates. The odds ratio value for the highest quintile of plasma vitamin E is: 4.2 (1.9-9.0).
Liposoluble vitamins and lipid parameters in breast cancer. A joint study in northern Italy and southern France / M. Gerber, F. Cavallo, E. Marubini, S. Richardson, A. Barbieri, E. Capitelli, A. Costa, A. Crastes de Paulet, P. Crastes de Paulet, A. Decarli. - In: INTERNATIONAL JOURNAL OF CANCER. - ISSN 0020-7136. - 42:4(1988 Oct 15), pp. 489-494.
|Titolo:||Liposoluble vitamins and lipid parameters in breast cancer. A joint study in northern Italy and southern France|
|Parole Chiave:||France; Vitamin E; Vitamin A; Lipids; Humans; Adult; Breast Neoplasms; Middle Aged; Diet; Italy; Female|
|Settore Scientifico Disciplinare:||Settore MED/01 - Statistica Medica|
|Data di pubblicazione:||15-ott-1988|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1002/ijc.2910420403|
|Appare nelle tipologie:||01 - Articolo su periodico|