One hundred and seventy-two hyperplastic and neoplastic epithelial lesions from 8 different mammalian and 1 avian species have been tested with an immunohistochemical technique to detect papillomavirus structural antigens. Selected lesions were diagnosed histologically as papilloma, fibropapilloma, equine sarcoid, squamous cell carcinoma, basalioma, epulis, keratoacanthoma, trichoepithelioma, pilomatrixoma, epidermal inclusion cyst, and hyperkeratotic or acanthotic epidermal lesions. Positive nuclear staining was detected in 14 out of 23 papillomas, 8 out of 32 fibropapillomas and in 1 out of 3 hyperplastic epidermal lesions. Positive samples were found in 5 of 8 mammalian species. Selected samples were also examined by transmission electron microscopy. In 4 samples papillomavirus was seen. In two other samples, negative with immunoperoxidase technique, papovavirus-like particles were observed.
Immunohistochemical detection of papillomavirus structural antigens in animal hyperplastic and neoplastic epithelial lesions / G. Sironi, M. Caniatti, E. Scanziani. - In: JOURNAL OF VETERINARY MEDICINE SERIES A. - ISSN 0931-184X. - 37:10(1990 Dec), pp. 760-770.
|Titolo:||Immunohistochemical detection of papillomavirus structural antigens in animal hyperplastic and neoplastic epithelial lesions|
SIRONI, GIUSEPPE (Primo)
CANIATTI, MARIO (Secondo)
SCANZIANI, EUGENIO (Ultimo)
|Parole Chiave:||Animals ; Neoplasms ; Hyperplasia ; Precancerous Conditions ; Mammals ; Bird Diseases ; Papillomaviridae ; Antigens, Viral ; Birds ; Immunohistochemistry|
|Settore Scientifico Disciplinare:||Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria|
|Data di pubblicazione:||dic-1990|
|Appare nelle tipologie:||01 - Articolo su periodico|