New quaternary ammonium polymers, which in a previous work had shown relevant antibacterial properties, have been investigated as regards to their hemolytic activity (HA) in comparison with a low molecular weight commercial antibacterial agent, Steramine G (SG). All polymers exhibit negligible, or at most modest, HA at dosages and contact times at which SG is strongly hemolytic.
A COMPARISON BETWEEN THE HEMOLYTIC AND ANTIBACTERIAL ACTIVITIES OF NEW QUATERNARY AMMONIUM POLYMERS / Marchisio, M.A. Null, B. P., L. T., F. P., E. Ranucci, N. M.. - In: JOURNAL OF BIOMATERIALS SCIENCE POLYMER EDITION. - ISSN 0920-5063. - 6:6(1994), pp. 533-539.
A COMPARISON BETWEEN THE HEMOLYTIC AND ANTIBACTERIAL ACTIVITIES OF NEW QUATERNARY AMMONIUM POLYMERS
E. Ranucci;
1994
Abstract
New quaternary ammonium polymers, which in a previous work had shown relevant antibacterial properties, have been investigated as regards to their hemolytic activity (HA) in comparison with a low molecular weight commercial antibacterial agent, Steramine G (SG). All polymers exhibit negligible, or at most modest, HA at dosages and contact times at which SG is strongly hemolytic.
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