We report on a 62-year-old woman who developed a severe aplastic anemia requiring frequent packed red cell and platelet transfusions. Since conventional pharmacological therapy was ineffective, treatment with Cyclosporin A was started, resulting in a significant increase of leukocyte, platelet, and red cell counts. However, 5 months after the beginning of Cyclosporin A treatment, despite a past medical history not significant for clinical tuberculosis, the patient developed tubercular pericarditis. This report underlines the need for a careful follow-up of Cyclosporin A-treated patients aimed at a prompt diagnosis of possible infectious complications.

CYCLOSPORINE-A IN THE TREATMENT OF SEVERE APLASTIC-ANEMIA - DESCRIPTION OF A CASE COMPLICATED BY THE DEVELOPMENT OF TUBERCULAR PERICARDITIS DURING TREATMENT / E. POGLIANI, M. CORTELLARO, P. FOA, A. IURLO, E. POLLI. - In: AMERICAN JOURNAL OF HEMATOLOGY. - ISSN 0361-8609. - 30:4(1989), pp. 257-258. [10.1002/ajh.2830300413]

CYCLOSPORINE-A IN THE TREATMENT OF SEVERE APLASTIC-ANEMIA - DESCRIPTION OF A CASE COMPLICATED BY THE DEVELOPMENT OF TUBERCULAR PERICARDITIS DURING TREATMENT

P. FOA;
1989

Abstract

We report on a 62-year-old woman who developed a severe aplastic anemia requiring frequent packed red cell and platelet transfusions. Since conventional pharmacological therapy was ineffective, treatment with Cyclosporin A was started, resulting in a significant increase of leukocyte, platelet, and red cell counts. However, 5 months after the beginning of Cyclosporin A treatment, despite a past medical history not significant for clinical tuberculosis, the patient developed tubercular pericarditis. This report underlines the need for a careful follow-up of Cyclosporin A-treated patients aimed at a prompt diagnosis of possible infectious complications.
Settore MED/06 - Oncologia Medica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/188303
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