The [2 + 2] Staudinger cycloaddition between the C=N double bond of 2,3-dihydrobenzoxazepines 2 and 6 and a series of acetyl chlorides gave the azetidino[4,1-d][1,4]benzo oxazepines 3 and 7, 8, respectively. In the case of enantiopure 6, the cycloaddition diastereoselectivity was markedly dependent from the substituent α to the imine.

The [2+2] Staudinger cycloadditive route to enantiopure azetidino[4,1-d][1,4]benzooxazepines / P. Del Buttero, G. Molteni, A. Papagni, L. Miozzo. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 15:16(2004 Aug 23), pp. 2555-2559. [10.1016/j.tetasy.2004.06.037]

The [2+2] Staudinger cycloadditive route to enantiopure azetidino[4,1-d][1,4]benzooxazepines

P. Del Buttero;G. Molteni;
2004-08-23

Abstract

The [2 + 2] Staudinger cycloaddition between the C=N double bond of 2,3-dihydrobenzoxazepines 2 and 6 and a series of acetyl chlorides gave the azetidino[4,1-d][1,4]benzo oxazepines 3 and 7, 8, respectively. In the case of enantiopure 6, the cycloaddition diastereoselectivity was markedly dependent from the substituent α to the imine.
Settore CHIM/06 - Chimica Organica
Article (author)
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S0957416604004847-main.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 283.73 kB
Formato Adobe PDF
283.73 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/187895
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 20
  • ???jsp.display-item.citation.isi??? 14
social impact