The importance of matrix metalloproteinases in angiogenesis, tumor growth, and metastasis is well known. However, little is known about the role of matrix metalloproteinases in the formation of hemangiomas and about the possible therapeutic use of matrix metalloproteinase inhibitors in aggressive vascular tumors.

Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases / G. Taraboletti, A. Garofalo, D. Belotti, T. Drudis, P. Borsotti, E. Scanziani, P. D. Brown, R. Giavazzi. - In: JOURNAL OF THE NATIONAL CANCER INSTITUTE. - ISSN 0027-8874. - 87:4(1995 Feb 15), pp. 293-8-298.

Inhibition of angiogenesis and murine hemangioma growth by batimastat, a synthetic inhibitor of matrix metalloproteinases

E. Scanziani;
1995-02-15

Abstract

The importance of matrix metalloproteinases in angiogenesis, tumor growth, and metastasis is well known. However, little is known about the role of matrix metalloproteinases in the formation of hemangiomas and about the possible therapeutic use of matrix metalloproteinase inhibitors in aggressive vascular tumors.
Neoplasm Invasiveness; Animals; Dose-Response Relationship, Drug; Hemangioendothelioma; Mice; Thiophenes; Neovascularization, Pathologic; Time Factors; Phenylalanine; Metalloendopeptidases; Female
Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria
JOURNAL OF THE NATIONAL CANCER INSTITUTE
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/187859
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