The diastereoselective cycloaddition of the nitrilimine 2 with enantiopure acrylamides 3 was exploited to obtain enantiopure 4,5-dihydropyrazoles 4 and 5. Basic hydrolysis of the cycloadducts gave the dicarboxy derivatives 6 and 7 or 8 and 9, which are of potential interest as new chiral building blocks. (C) 2002 Elsevier Science Ltd. All rights reserved.

Diastereoselective cycloadditions of nitrilimines to enantiopure acrylamides / L. Garanti, G. Molteni, T. Pilati. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 13:12(2002), pp. 1285-1289. [10.1016/S0957-4166(02)00258-6]

Diastereoselective cycloadditions of nitrilimines to enantiopure acrylamides

G. Molteni;
2002

Abstract

The diastereoselective cycloaddition of the nitrilimine 2 with enantiopure acrylamides 3 was exploited to obtain enantiopure 4,5-dihydropyrazoles 4 and 5. Basic hydrolysis of the cycloadducts gave the dicarboxy derivatives 6 and 7 or 8 and 9, which are of potential interest as new chiral building blocks. (C) 2002 Elsevier Science Ltd. All rights reserved.
Settore CHIM/06 - Chimica Organica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/187778
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