The incidence of secondary malignancies following chemotherapy is progressively increasing, mostly due to prolonged survival of patients treated for primary cancer. So far, only 3 cases of solid cancer following busulphan administration have been reported. We describe the case of a patient who developed a renal cancer after 4 years of busulphan treatment for chronic myeloid leukemia. Immunosuppression rather than mutagenesis seems to be responsible for the emergence of second solid cancers in patients receiving busulphan.
RENAL-CANCER AFTER BUSULFAN TREATMENT FOR CHRONIC MYELOID-LEUKEMIA - A CASE-REPORT / A. LURLO, P. FOA, M. SALA, A. MAIOLO. - In: TUMORI. - ISSN 0300-8916. - 79:4(1993), pp. 278-279.
RENAL-CANCER AFTER BUSULFAN TREATMENT FOR CHRONIC MYELOID-LEUKEMIA - A CASE-REPORT
P. FOA;
1993
Abstract
The incidence of secondary malignancies following chemotherapy is progressively increasing, mostly due to prolonged survival of patients treated for primary cancer. So far, only 3 cases of solid cancer following busulphan administration have been reported. We describe the case of a patient who developed a renal cancer after 4 years of busulphan treatment for chronic myeloid leukemia. Immunosuppression rather than mutagenesis seems to be responsible for the emergence of second solid cancers in patients receiving busulphan.
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