A new series of cephalosporins having in the C-7 side chain a phenyl- or a phenoxyacetamido group bearing an oxyiminomethyl function in the ortho-position of the aromatic ring was prepared. Their in vitro activity was tested against both Gram+ and Gram- strains. (C) 1998 Elsevier Science S.A. All rights reserved.
Synthesis and activity of cephalosporins containing an oxyiminomethylene functionality in the ortho-position of a phenyl- or phenoxyacetic acid C-7 side chain substituent / D. Albanese, D. Landini, M. Leone, M. Penso, M. Zenoni. - In: IL FARMACO. - ISSN 0014-827X. - 53:10-11(1998), pp. 709-717.
Titolo: | Synthesis and activity of cephalosporins containing an oxyiminomethylene functionality in the ortho-position of a phenyl- or phenoxyacetic acid C-7 side chain substituent |
Autori: | ALBANESE, DOMENICO (Primo) LANDINI, DARIO (Secondo) |
Parole Chiave: | β-lactam antibiotics; Oxyacetamido cephalosporins; Oxyiminomethylene cephalosporins; Phase transfer catalysis |
Settore Scientifico Disciplinare: | Settore CHIM/04 - Chimica Industriale |
Data di pubblicazione: | 1998 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S0014-827X(98)00112-8 |
Appare nelle tipologie: | 01 - Articolo su periodico |
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