We investigated the presence of human T-lymphotropic virus type 2 (HTLV- 2) DNA in the peripheral blood mononuclear cell subsets obtained from 18 patients coinfected with human immunodeficiency virus type 1 and HTLV-2, 6 of whom also had predominantly sensory polyneuropathy (PSP). HTLV-2 DNA and RNA were found in CD8- and CD19-positive cells, and, for patients with PSP, in CD14-positive cells as well. Furthermore, the patients with PSP had higher proviral loads than those without PSP.
Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy / G. Zehender, L. Meroni, S. Varchetta, C. De Maddalena, B. Cavalli, M. Gianotto, A. B. Bosisio, C. Colasante, G. Rizzardini, M. Moroni, M. Galli. - In: JOURNAL OF VIROLOGY. - ISSN 0022-538X. - 72:9(1998 Sep), pp. 7664-7668.
|Titolo:||Human T-lymphotropic virus type 2 (HTLV-2) provirus in circulating cells of the monocyte/macrophage lineage in patients dually infected with human immunodeficiency virus type 1 and HTLV-2 and having predominantly sensory polyneuropathy|
ZEHENDER, GIANGUGLIELMO (Primo)
MORONI, MAURO (Penultimo)
GALLI, MASSIMO (Ultimo)
|Parole Chiave:||Sensitivity and Specificity; HTLV-II Infections; Macrophages; Human T-lymphotropic virus 2; Humans; RNA, Viral; HIV-1; Evaluation Studies as Topic; Polymerase Chain Reaction; DNA, Viral; Peripheral Nervous System Diseases; AIDS-Related Opportunistic Infections; Adult; Mathematical Computing; Middle Aged; Monocytes; Deltaretrovirus Antibodies; Proviruses; Female; Male; T-Lymphocyte Subsets|
|Settore Scientifico Disciplinare:||Settore MED/17 - Malattie Infettive|
|Data di pubblicazione:||set-1998|
|Appare nelle tipologie:||01 - Articolo su periodico|