Vicinal halofluorides have been prepared from the corresponding alkenes by reaction with a stoicheiometric amount of Bu4N+H2F3- as a source of fluoride anion and an excess of an N-halosuccinimide (NXS). The reaction products are obtained in good yields, with a prevalent Markownikoff regiochemistry. Olefins containing hydroxy, epoxy, acetoxy and alkoxy groups do not undergo side reactions under these reaction conditions.
TETRABUTYLAMMONIUM DIHYDROGENTRIFLUORIDE - AN EFFECTIVE SOURCE OF FLUORIDE-ION FOR HALOFLUORINATION OF ALKENES / D. Albanese, D. Landini, M. Penso, M. Pratelli. - In: GAZZETTA CHIMICA ITALIANA. - ISSN 0016-5603. - 121:12(1991), pp. 537-541.
TETRABUTYLAMMONIUM DIHYDROGENTRIFLUORIDE - AN EFFECTIVE SOURCE OF FLUORIDE-ION FOR HALOFLUORINATION OF ALKENES
D. AlbanesePrimo
;D. LandiniSecondo
;
1991
Abstract
Vicinal halofluorides have been prepared from the corresponding alkenes by reaction with a stoicheiometric amount of Bu4N+H2F3- as a source of fluoride anion and an excess of an N-halosuccinimide (NXS). The reaction products are obtained in good yields, with a prevalent Markownikoff regiochemistry. Olefins containing hydroxy, epoxy, acetoxy and alkoxy groups do not undergo side reactions under these reaction conditions.
Pubblicazioni consigliate
I metadati presenti in AIR sono rilasciati con licenza CCO mentre i file delle pubblicazioni sono rilasciati con licenza CC BY-SA, salvo diversa indicazione. In caso di violazione di copyright, contattare l'assistenza di AIR
