The backward effects of left ventricular dysfunction include alterations in alveolar-capillary gas transfer and ventilation-perfusion coupling. Because the angiotensin-converting enzyme (ACE) is highly concentrated in the vascular endothelium of the lungs, we examined whether ACE inhibitors may influence the pulmonary function in patients with congestive heart failure.

Angiotensin-converting enzyme inhibition facilitates alveolar-capillary gas transfer and improves ventilation-perfusion coupling in patients with left ventricular dysfunction / M. Guazzi, G. Melzi, G. C. Marenzi, P. Agostoni. - In: CLINICAL PHARMACOLOGY & THERAPEUTICS. - ISSN 0009-9236. - 65:3(1999 Mar), pp. 319-27-327.

Angiotensin-converting enzyme inhibition facilitates alveolar-capillary gas transfer and improves ventilation-perfusion coupling in patients with left ventricular dysfunction

M. Guazzi
Primo
;
P. Agostoni
Ultimo
1999-03

Abstract

The backward effects of left ventricular dysfunction include alterations in alveolar-capillary gas transfer and ventilation-perfusion coupling. Because the angiotensin-converting enzyme (ACE) is highly concentrated in the vascular endothelium of the lungs, we examined whether ACE inhibitors may influence the pulmonary function in patients with congestive heart failure.
Respiratory Function Tests; Heart Failure; Humans; Exercise; Capillaries; Cardiomyopathies; Matched-Pair Analysis; Exercise Test; Oxygen; Enalapril; Ventilation-Perfusion Ratio; Adult; Treatment Outcome; Case-Control Studies; Ventricular Dysfunction, Left; Angiotensin-Converting Enzyme Inhibitors; Middle Aged; Time Factors; Pulmonary Alveoli; Female; Male; Carbon Dioxide
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/186838
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