We have studied by radioimmunoassay the prevalence of antibody to hepatitis A virus in 436 randomly selected individuals of Milan according to age and sex. Taken together, 70% of subjects provided serological evidence of exposure to HAV. Both sexes resulted similarly immunized (69.7% females and 70.7% males). The anti-HAV prevalence was found to be directly related to age, being on the increase from childhood to adulthood and reaching its peak (9l.5%) in people over fifty. An analysis of the distribution of anti-HAV according to presence or absence of anti-HBs in induviduals under 30 years, revealed that anti-HAV was detectable more frequently in individuals anti-HBs positive than in those without such evidence in sera (71.4% versus 39.7%; P less than 0.01). Finally, 96 sera from children and adolescents of low socioeconomic standard of living were also investigated. In these subjects anti-HAV prevalence was found to be higher than in their counterparts randomly slected from general population.
Prevalence of antibody to hepatitis A virus in healthy individuals of Milan / A.R. ZANETTI, P. FERRONI. - In: BOLLETTINO DELL'ISTITUTO SIEROTERAPICO MILANESE. - ISSN 0021-2547. - 57:4(1978), pp. 523-527.
|Titolo:||Prevalence of antibody to hepatitis A virus in healthy individuals of Milan|
ZANETTI, ALESSANDRO REMO (Primo)
|Settore Scientifico Disciplinare:||Settore MED/42 - Igiene Generale e Applicata|
|Data di pubblicazione:||1978|
|Appare nelle tipologie:||01 - Articolo su periodico|