In recent years, considerable interest has developed in recognizing antigenic specificities additional to the surface antigen in the sera of patients infected with hepatitis B infection. The presence of the e-antigen appears to be invariably associated with ongoing virus replication. In the present study, sera from acute and chronically infected patients have been examined for both e-antigen and antibody, and the results correlated with the presence of complete 42-nm virus particles. In addition, some preliminary results illustrating the possible physicochemical nature of e-antigen are presented.
The nature of hepatitis B e antigen / C.R. HOWARD, A.R. ZANETTI, A.J. ZUCKERMAN. - In: JOURNAL OF MEDICAL VIROLOGY. - ISSN 0146-6615. - 3:1(1978), pp. 59-66.
The nature of hepatitis B e antigen
A.R. ZANETTISecondo
;
1978
Abstract
In recent years, considerable interest has developed in recognizing antigenic specificities additional to the surface antigen in the sera of patients infected with hepatitis B infection. The presence of the e-antigen appears to be invariably associated with ongoing virus replication. In the present study, sera from acute and chronically infected patients have been examined for both e-antigen and antibody, and the results correlated with the presence of complete 42-nm virus particles. In addition, some preliminary results illustrating the possible physicochemical nature of e-antigen are presented.
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