Recent research has found that entry of non-syncytium-inducing (NSI), monocyte-macrophage-tropic HIV-1 isolates requires binding to both CD4 and CCR5 receptors, and that delta 32/delta 32 homozygous individuals are protected against infection.
Homozygous delta 32 deletion of the CCR-5 chemokine receptor gene in an HIV-1-infected patient / C. Balotta, P. Bagnarelli, M. Violin, A. L. Ridolfo, D. Zhou, A. Berlusconi, S. Corvasce, M. Corbellino, M. Clementi, M. Clerici, M. Moroni, M. Galli. - In: AIDS. - ISSN 0269-9370. - 11:10(1997 Aug), pp. F67-71.
Homozygous delta 32 deletion of the CCR-5 chemokine receptor gene in an HIV-1-infected patient
C. BalottaPrimo
;M. Violin;S. Corvasce;M. Clerici;M. MoroniPenultimo
;M. GalliUltimo
1997-08
Abstract
Recent research has found that entry of non-syncytium-inducing (NSI), monocyte-macrophage-tropic HIV-1 isolates requires binding to both CD4 and CCR5 receptors, and that delta 32/delta 32 homozygous individuals are protected against infection.
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