The effects induced in biological samples by free radicals generated during short periods (less than or equal to 5 min) of ultrasound irradiation have been investigated by following the decay kinetics of the electron paramagnetic resonance signal of the piperidine nitroxide 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPOL) in rat heart homogenates. Different kinetic models have been evaluated in order to identify the reactions involved in nitroxide decay. The results obtained indicate that sonication, however short its duration, significantly alters components of the homogenate playing a major role in nitroxide decay, thus substantially modifying the kinetics of the process. (C) 1997 Elsevier Science Ltd.

Effects of ultrasound irradiation on the properties of biological homogenates / C. Oliva, R. Morelli, E. Monti. - In: RADIATION PHYSICS AND CHEMISTRY. - ISSN 0969-806X. - 49:5(1997), pp. 553-557.

Effects of ultrasound irradiation on the properties of biological homogenates

C. Oliva
Primo
;
1997

Abstract

The effects induced in biological samples by free radicals generated during short periods (less than or equal to 5 min) of ultrasound irradiation have been investigated by following the decay kinetics of the electron paramagnetic resonance signal of the piperidine nitroxide 4-hydroxy-2,2,6,6-tetramethylpiperidine-N-oxyl (TEMPOL) in rat heart homogenates. Different kinetic models have been evaluated in order to identify the reactions involved in nitroxide decay. The results obtained indicate that sonication, however short its duration, significantly alters components of the homogenate playing a major role in nitroxide decay, thus substantially modifying the kinetics of the process. (C) 1997 Elsevier Science Ltd.
Settore CHIM/02 - Chimica Fisica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/186387
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