A family of five regioisomenc protected fucosyllactoses has been synthesised in only 14 overall steps from the easily available benzyllactoside. The adopted strategy combines enzymatic regioselective protection, introduction of ortho-gonal protecting groups and regioselective glycosylations on partially unprotected lactosidic acceptors.
Lipase-catalysed regioselective acylations in combination with regioselective glycosylations as a strategy for the synthesis of oligosaccharides: Synthesis of a series of fucosyllactose building blocks / A. Rencurosi, L. Poletti, G. Russo, L. Lay. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - 2003:9(2003), pp. 1672-1680. [10.1002/ejoc.200200425]
Lipase-catalysed regioselective acylations in combination with regioselective glycosylations as a strategy for the synthesis of oligosaccharides: Synthesis of a series of fucosyllactose building blocks
L. PolettiSecondo
;G. RussoPenultimo
;L. Lay
2003
Abstract
A family of five regioisomenc protected fucosyllactoses has been synthesised in only 14 overall steps from the easily available benzyllactoside. The adopted strategy combines enzymatic regioselective protection, introduction of ortho-gonal protecting groups and regioselective glycosylations on partially unprotected lactosidic acceptors.Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.