A 71-year-old woman presented with multiple, flesh-colored, papular lesions on the left dorsal side of the hand which had erupted 5 years earlier. No cafè-au-lait spots, freckles, or Lisch nodules were detected. Family history did not disclose neurofibromas or abnormal pigmentation. Two biopsy specimens of the lesions showed circumscribed, non-encapsulated neurofibromas. Segmental neurofibromatosis is characterized by the unilateral, segmental appearance of neurofibromas and/or cafè-au-lait spots in the absence of genetic transmission. The authors discuss the significance of localized multiple cutaneous neurofibromas in the absence of family history and suggest the possibility of a cutaneous hamartoma.
Regional eruptive neurofibromas / R. Betti, A. Cerri, L. Gualandri, L. Moneghini, C. Crosti. - In: JOURNAL OF DERMATOLOGY. - ISSN 0385-2407. - 24:3(1997 Mar), pp. 198-201.
Titolo: | Regional eruptive neurofibromas |
Autori: | CERRI, AMILCARE (Secondo) CROSTI, CARLO (Ultimo) |
Parole Chiave: | Skin; Humans; Neurofibromatoses; Aged; Hand; Skin Neoplasms; Female |
Settore Scientifico Disciplinare: | Settore MED/35 - Malattie Cutanee e Veneree |
Data di pubblicazione: | mar-1997 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1111/j.1346-8138.1997.tb02772.x |
Appare nelle tipologie: | 01 - Articolo su periodico |