The antimicrobial susceptibility of 68 Staphylococcus aureus isolates collected during 2004 from milk of cows affected by subclinical mastitis was examined. The anti- microbial agents tested were the β-lactams, penicillin G, amoxicillin, ampicillin, cloxacillin, amoxicillin + cla- vulanate, cephalonium, and cefoperazone; and other drugs including lincomycin, oxytetracycline, doxycy- cline, and kanamycin. Minimum inhibitory concentra- tions recorded show that only certain β-lactamase–re- sistant penicillins (specifically cloxacillin) or penicillin combinations (amoxicillin + clavulanate) were consis- tently effective against Staph. aureus, whereas the other β-lactam derivatives and drugs from other phar- macological groups were either moderately effective or ineffective. Thus, β-lactamase–resistant penicillins are to be considered the antimicrobial agents of choice for treatment of bovine mastitis resulting from infection by Staph. aureus. Key words: Staphylococcus aureus, bovine, minimum inhibitory concentration

Antimicrobial drug susceptibility of Staphylococcus aureus isolated from subclinical bovine mastitis in Italy / P. Moroni, G. Pisoni, M. Antonini, R.E. Villa, P. Boettcher, S. Carli. - In: JOURNAL OF DAIRY SCIENCE. - ISSN 0022-0302. - 89:8(2006), pp. 2973-2976. [10.3168/jds.S0022-0302(06)72569-3]

Antimicrobial drug susceptibility of Staphylococcus aureus isolated from subclinical bovine mastitis in Italy

P. Moroni;G. Pisoni;R.E. Villa;S. Carli
2006

Abstract

The antimicrobial susceptibility of 68 Staphylococcus aureus isolates collected during 2004 from milk of cows affected by subclinical mastitis was examined. The anti- microbial agents tested were the β-lactams, penicillin G, amoxicillin, ampicillin, cloxacillin, amoxicillin + cla- vulanate, cephalonium, and cefoperazone; and other drugs including lincomycin, oxytetracycline, doxycy- cline, and kanamycin. Minimum inhibitory concentra- tions recorded show that only certain β-lactamase–re- sistant penicillins (specifically cloxacillin) or penicillin combinations (amoxicillin + clavulanate) were consis- tently effective against Staph. aureus, whereas the other β-lactam derivatives and drugs from other phar- macological groups were either moderately effective or ineffective. Thus, β-lactamase–resistant penicillins are to be considered the antimicrobial agents of choice for treatment of bovine mastitis resulting from infection by Staph. aureus. Key words: Staphylococcus aureus, bovine, minimum inhibitory concentration
Settore VET/07 - Farmacologia e Tossicologia Veterinaria
Settore VET/05 - Malattie Infettive degli Animali Domestici
JOURNAL OF DAIRY SCIENCE
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/18589
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