Terminal respiratory failure was reversed in three patients with a combination of extra-corporeal CO2 removal through a membrane lung and oxygen diffusion into the diseased lungs between mechanical breaths induced at a frequency of 2-3/min. The technique seems to prevent the pulmonary barotrauma and extrapulmonary derangements caused by conventional mechanical ventilation.
Treatment of acute respiratory failure with low-frequency positive-pressure ventilation and extracorporeal removal of CO2 / L. Gattinoni, A. Agostoni, A. Pesenti, A. Pelizzola, G. P. Rossi, M. Langer, S. Vesconi, L. Uziel, U. Fox, F. Longoni, T. Kolobow, G. Damia. - In: THE LANCET. - ISSN 0140-6736. - 2:8189(1980 Aug 09), pp. 292-4-294. [10.1016/S0140-6736(80)90237-8]
Treatment of acute respiratory failure with low-frequency positive-pressure ventilation and extracorporeal removal of CO2
L. Gattinoni;A. Pesenti;M. Langer;
1980
Abstract
Terminal respiratory failure was reversed in three patients with a combination of extra-corporeal CO2 removal through a membrane lung and oxygen diffusion into the diseased lungs between mechanical breaths induced at a frequency of 2-3/min. The technique seems to prevent the pulmonary barotrauma and extrapulmonary derangements caused by conventional mechanical ventilation.
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