The chloroperoxidase-catalyzed and horseradish peroxidase catalyzed oxidations of sulfides by tert-butyl and other peroxides have been investigated. The former metal enzyme afforded the corresponding sulfoxides having R absolute configuration in up to 92% enantiomeric excess (ee), whereas the latter gave racemic products. The various factors that control the enantioselectivity of the oxygenation have been examined.

Enantioselective oxidations of sulfides catalyzed by chloroperoxidase / S. Colonna, N. Gaggero, A. Manfredi, L. Casella, M.Gullotti, G. Carrea, P. Pasta. - In: BIOCHEMISTRY. - ISSN 0006-2960. - 29:46(1990), pp. 10465-10468.

Enantioselective oxidations of sulfides catalyzed by chloroperoxidase

S. Colonna;N. Gaggero;A. Manfredi;
1990

Abstract

The chloroperoxidase-catalyzed and horseradish peroxidase catalyzed oxidations of sulfides by tert-butyl and other peroxides have been investigated. The former metal enzyme afforded the corresponding sulfoxides having R absolute configuration in up to 92% enantiomeric excess (ee), whereas the latter gave racemic products. The various factors that control the enantioselectivity of the oxygenation have been examined.
peroxidase; sulfide; oxidation; Horseradish Peroxidase; sulfoxides; chloroperoxidase
Settore CHIM/06 - Chimica Organica
BIOCHEMISTRY
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/185347
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