The hydropathicity of a series of compounds active as allosteric modulators at the M2 musca-rinic receptors was calculated and projected on the molecular surface. An analysis of the rela-tionships between conformational and local hydropathicity properties was also performed.
Molecular Hydropathicity Index: application to a series of allosteric modulators of the M2 receptors / G. Vistoli, A. Pedretti, A.M. Villa, L. Villa, U. Holzgrabe, A. Cambareri. - In: ANALUSIS. - ISSN 0365-4877. - 27:1(1999), pp. 32-37.
Molecular Hydropathicity Index: application to a series of allosteric modulators of the M2 receptors
G. VistoliPrimo
;A. PedrettiSecondo
;L. Villa;
1999
Abstract
The hydropathicity of a series of compounds active as allosteric modulators at the M2 musca-rinic receptors was calculated and projected on the molecular surface. An analysis of the rela-tionships between conformational and local hydropathicity properties was also performed.
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