In a case-control study to evaluate risk factors for endometrial cancer, obesity, history of various diseases, reproductive and menstrual characteristics, marital status, education, and lifetime use of female hormones were examined in 173 histologically proven endometrial cancers and 347 controls. Obesity, non-contraceptive oestrogen use, late menopause, low parity and history of uterine fibromyomas were associated with an increased risk of endometrial cancer. The relative risks of obesity and oestrogen use seem to fit well for an additive model. Histological differentiation was positively correlated both to oestrogen use and to level of overweight, supporting the hypothesis of a specific role of oestrogens in endometrial cancer.
Oestrogens and obesity as risk factors for endometrial cancer in Italy / C. La Vecchia, S. Franceschi, G. Gallus, A. Decarli, E. Colombo, C. Mangioni, G. Tognoni. - In: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. - ISSN 0300-5771. - 11:2(1982), pp. 120-126. [10.1093/ije/11.2.120]
Oestrogens and obesity as risk factors for endometrial cancer in Italy
C. La Vecchia;A. Decarli;
1982
Abstract
In a case-control study to evaluate risk factors for endometrial cancer, obesity, history of various diseases, reproductive and menstrual characteristics, marital status, education, and lifetime use of female hormones were examined in 173 histologically proven endometrial cancers and 347 controls. Obesity, non-contraceptive oestrogen use, late menopause, low parity and history of uterine fibromyomas were associated with an increased risk of endometrial cancer. The relative risks of obesity and oestrogen use seem to fit well for an additive model. Histological differentiation was positively correlated both to oestrogen use and to level of overweight, supporting the hypothesis of a specific role of oestrogens in endometrial cancer.File | Dimensione | Formato | |
---|---|---|---|
Oestrogens- obesity-endometrial LA VECCHIA 1672-82.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
458.76 kB
Formato
Adobe PDF
|
458.76 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.