An efficient preparation of 18-benzyloxy-8(9)-podocarpen-14-one, 3a, a key intermediate for a diastereoselective synthesis of the bicyclo[2.2.2]octan-2-ol, 1, precursor of the tetracyclic diol stemarin, 2, is described. The approach outlined can be, in principle, applied to the preparation of related compounds.

STUDIES FOR A DIASTEREOSELECTIVE SYNTHESIS OF THE TETRACYCLIC DITERPENIC DIOL STEMARIN - AN IMPROVED PROCEDURE FOR THE SYNTHESIS OF 8(9)-PODOCARPEN-14-ONES - THE TOTAL SYNTHESIS OF 18-BENZYLOXY-8(9)-PODOCARPEN-14-ONE AND RELATED STUDIES / S. Antonaroli, M. Berettoni, G. Cifarelli, A. Lupi, R. Bettolo, S. Romeo. - In: GAZZETTA CHIMICA ITALIANA. - ISSN 0016-5603. - 122:2(1992), pp. 55-59.

STUDIES FOR A DIASTEREOSELECTIVE SYNTHESIS OF THE TETRACYCLIC DITERPENIC DIOL STEMARIN - AN IMPROVED PROCEDURE FOR THE SYNTHESIS OF 8(9)-PODOCARPEN-14-ONES - THE TOTAL SYNTHESIS OF 18-BENZYLOXY-8(9)-PODOCARPEN-14-ONE AND RELATED STUDIES

S. Romeo
Ultimo
1992

Abstract

An efficient preparation of 18-benzyloxy-8(9)-podocarpen-14-one, 3a, a key intermediate for a diastereoselective synthesis of the bicyclo[2.2.2]octan-2-ol, 1, precursor of the tetracyclic diol stemarin, 2, is described. The approach outlined can be, in principle, applied to the preparation of related compounds.
Settore CHIM/08 - Chimica Farmaceutica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/185109
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