Several optically active (R)- and (S)-(E)-4-hydroxyalk-2-enoic acids, metabolites of bioactive compounds of lipid peroxidation, were prepared from the corresponding racemic methyl esters by enantioselective hydrolysis mediated by porcine pancreas lipase and porcine liver esterase.
PREPARATION OF (R)-(E)-4-HYDROXY-2-UNSATURATED AND (S)-(E)-4-HYDROXY-2-UNSATURATED ACIDS BY ASYMMETRIC HYDROLYSIS OF THEIR RACEMIC ESTERS / P. ALLEVI, M. ANASTASIA, P. CIUFFREDA, A. SANVITO. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 4:7(1993), pp. 1397-1400. [10.1016/S0957-4166(00)80324-9]
PREPARATION OF (R)-(E)-4-HYDROXY-2-UNSATURATED AND (S)-(E)-4-HYDROXY-2-UNSATURATED ACIDS BY ASYMMETRIC HYDROLYSIS OF THEIR RACEMIC ESTERS
P. AlleviPrimo
;M. AnastasiaSecondo
;P. CiuffredaPenultimo
;
1993
Abstract
Several optically active (R)- and (S)-(E)-4-hydroxyalk-2-enoic acids, metabolites of bioactive compounds of lipid peroxidation, were prepared from the corresponding racemic methyl esters by enantioselective hydrolysis mediated by porcine pancreas lipase and porcine liver esterase.File in questo prodotto:
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