Three hundred fifty-four evaluable cases of hydatidiform mole diagnosed from 1970 to 1979 in 10 regional hospitals in Lombardy are analyzed in the present report. Twenty-six (7.3%) of the patients developed persistent trophoblastic disease. Younger (less than 20 years) and older (40 years or more) age at diagnosis, a large-for-dates uterus, and ovarian enlargement were associated with an increased risk of developing persistent trophoblastic disease. Twenty-three (9%) cases of persistent trophoblastic disease were observed among 250 women not prophylactically treated, but only in 3 (3%) among 104 who received prophylactic chemotherapy. High-risk groups are defined and the role of prophylactic chemotherapy is discussed.
Management of gestational trophoblastic disease: results of a cooperative study / M. Fasoli, E. Ratti, S. Franceschi, C. La Vecchia, S. Pecorelli, C. Mangioni. - In: OBSTETRICS AND GYNECOLOGY. - ISSN 0029-7844. - 60:2(1982 Aug), pp. 205-209.
Management of gestational trophoblastic disease: results of a cooperative study
C. La Vecchia;
1982
Abstract
Three hundred fifty-four evaluable cases of hydatidiform mole diagnosed from 1970 to 1979 in 10 regional hospitals in Lombardy are analyzed in the present report. Twenty-six (7.3%) of the patients developed persistent trophoblastic disease. Younger (less than 20 years) and older (40 years or more) age at diagnosis, a large-for-dates uterus, and ovarian enlargement were associated with an increased risk of developing persistent trophoblastic disease. Twenty-three (9%) cases of persistent trophoblastic disease were observed among 250 women not prophylactically treated, but only in 3 (3%) among 104 who received prophylactic chemotherapy. High-risk groups are defined and the role of prophylactic chemotherapy is discussed.File | Dimensione | Formato | |
---|---|---|---|
Management_of_Gestational_Trophoblastic_Disease_.13.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
387.07 kB
Formato
Adobe PDF
|
387.07 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.