Eight families with multiple occurrence of epithelial ovarian cancer (22 cases) are described. A high proportion of serous and undifferentiated carcinoma, bilateral ovarian involvement, multiple primary cancers, and unfavorable prognosis was found, in agreement with reports concerning 28 previously described families. The importance of family history evaluation and the utility of prophylactic oophorectomy in women from high-risk families are stressed.
Familial ovarian cancer: eight more families / S. Franceschi, C. La Vecchia, C. Mangioni. - In: GYNECOLOGIC ONCOLOGY. - ISSN 0090-8258. - 13:1(1982 Feb), pp. 31-36. [10.1016/0090-8258(82)90005-1]
Familial ovarian cancer: eight more families
C. La VecchiaSecondo
;
1982
Abstract
Eight families with multiple occurrence of epithelial ovarian cancer (22 cases) are described. A high proportion of serous and undifferentiated carcinoma, bilateral ovarian involvement, multiple primary cancers, and unfavorable prognosis was found, in agreement with reports concerning 28 previously described families. The importance of family history evaluation and the utility of prophylactic oophorectomy in women from high-risk families are stressed.
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