Reaction of bromonitrile oxide with N-BOC-allylamine, followed by hydrolysis with aqueous NaOH, isoxazolin-3-ol derivative 3, a key-intermediate in the synthesis of racemic as well optically pure R(-)- and S(+)-dihydromuscimol.
AN EASY SYNTHESIS OF DIHYDROMUSCIMOL / P. Caldirola, M. De Amici, C. De Micheli. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - 27:38(1986), pp. 4651-4652.
AN EASY SYNTHESIS OF DIHYDROMUSCIMOL
M. De AmiciSecondo
;C. De MicheliUltimo
1986
Abstract
Reaction of bromonitrile oxide with N-BOC-allylamine, followed by hydrolysis with aqueous NaOH, isoxazolin-3-ol derivative 3, a key-intermediate in the synthesis of racemic as well optically pure R(-)- and S(+)-dihydromuscimol.
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