Various (R)- and (S)-1-trimethylsilyl-1-alkyn-3-ols, chiral building units useful for the synthesis of biologically active compounds, have been efficiently resolved by enantioselective acetylation mediated by immobilized lipase PS. The resolution is applied to the synthesis of (R)- and (S)-5-octyl-2-(5H)-furanones
Lipase catalysed resolution of (R)- and (S)-1-trimethylsilyl-1-alkyn-3-ols: Useful intermediates for the synthesis of optically active gamma-lactones / P. Allevi, P. Ciuffreda, M. Anastasia. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 8:1(1997), pp. 93-99. [10.1016/S0957-4166(96)00475-2]
Titolo: | Lipase catalysed resolution of (R)- and (S)-1-trimethylsilyl-1-alkyn-3-ols: Useful intermediates for the synthesis of optically active gamma-lactones | |
Autori: | ALLEVI, PIETRO (Primo) CIUFFREDA, PIERANGELA (Secondo) ANASTASIA, MARIO (Ultimo) | |
Parole Chiave: | CHIRAL BUILDING BLOCKS ; ENANTIOSELECTIVE ACETYLATION ; ENZYMATIC ACETYLATION ; FURANONES | |
Settore Scientifico Disciplinare: | Settore BIO/10 - Biochimica | |
Data di pubblicazione: | 1997 | |
Rivista: | ||
Tipologia: | Article (author) | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1016/S0957-4166(96)00475-2 | |
Appare nelle tipologie: | 01 - Articolo su periodico |
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
Loading suggested articles...
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.