Peripheral blood mononuclear cells from human immunodeficiency virus seropositive (HIV+) individuals who did not exhibit symptoms of acquired immunodeficiency syndrome (AIDS) (Walter Reed Stage 1 patients) were tested for accessory cell function for presentation of recall antigens to autologous T lymphocytes and for presentation of HLA alloantigens to T lymphocytes from healthy, HIV- donors. Neither experimental model indicated a defect in accessory cell function at this early stage after HIV infection, although our study does not exclude the possibility of accessory cell dysfunction at a later stage of AIDS development.
Accessory cell function in asymptomatic, human immunodeficiency virus infected patients / M. Clerici, N.I. Stocks, R.A. Zajac, R.N. Boswell, G.M. Shearer. - In: CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY. - ISSN 0090-1229. - 54:2(1990), pp. 168-173.
|Titolo:||Accessory cell function in asymptomatic, human immunodeficiency virus infected patients|
CLERICI, MARIO SALVATORE (Primo)
|Settore Scientifico Disciplinare:||Settore MED/04 - Patologia Generale|
|Data di pubblicazione:||1990|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/0090-1229(90)90078-5|
|Appare nelle tipologie:||01 - Articolo su periodico|