Serum monoclonal anti-Myelin Associated Glycoprotein antibodies may be pathogenic in some patients with IgM paraprotein and demyelinating neuropathy. Immunotherapies aimed at reducing the level of these antibodies might be expected to be of benefit in the treatment of the neuropathy. Many potential therapies have been described in small trials, uncontrolled studies and case reports.
Immunotherapy for IgM anti-Myelin-Associated Glycoprotein paraprotein-associated peripheral neuropathies / M. P. Lunn, E. Nobile-Orazio. - In: COCHRANE DATABASE OF SYSTEMATIC REVIEWS. - ISSN 1469-493X. - :1(2003), p. CD002827.
Titolo: | Immunotherapy for IgM anti-Myelin-Associated Glycoprotein paraprotein-associated peripheral neuropathies |
Autori: | NOBILE-ORAZIO, EDUARDO (Ultimo) |
Parole Chiave: | Randomized Controlled Trials as Topic ; Myelin-Associated Glycoprotein ; Demyelinating Diseases ; Peripheral Nervous System Diseases ; Immunotherapy ; Humans ; Immunoglobulin M |
Settore Scientifico Disciplinare: | Settore MED/26 - Neurologia |
Data di pubblicazione: | 2003 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/14651858.CD002827 |
Appare nelle tipologie: | 01 - Articolo su periodico |
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